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Overview of main clinical studies for MASLD/MASH with GLP-1 receptor agonists and dual or triple agonists targeting glucagon/GIP/GLP-1 receptors Liraglutide Liraglutide, a once-daily GLP-1 receptor agonist with authorized indications for type 2 diabetes and obesity, was evaluated in the LEAN trial (NCT01237119), a phase 2 randomized controlled study enrolling 52 adults with biopsy-proven MASH [22]

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sPLS-DA highlighted a subset of nine metabolites that accurately classified Long COVID patients, including aKG, CMC, CML, creatine, fumarate, lactate, LDL particle size (LDL-Z), 2SC and tyrosine (Fig

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